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CAS 1405-20-5
Time:2019/10/14 10:05:21 Hit:791
Polymyxin B sulfate (Polymyxin B sulfate), the molecular formula is C56H100N16O17S. Polymyxin B is an anti-Gram-negative bacillus polypeptide antibiotic, which can change the membrane structure to leak small molecules and inhibit the growth of Gram-negative bacteria. Has a bactericidal effect on E. coli. Binds to the lipid A portion of bacterial lipopolysaccharides. Induces small holes in the outer cell membrane.
Chinese name: Polymyxin B sulfate
English name: Polymyxin B sulfate
Chinese alias: Polymyxin B sulfate, USP grade; Polymyxin B sulfate; Polymyxin B sulfate
English alias: PolymyxineBsulfate;MASTIMYXIN;POLYMYXIN B
CAS Number: 1405-20-5
Molecular formula: C56H100N16O17S
Molecular weight: 1301.56000
Accurate quality: 1300.72000
PSA: 573.64000
LogP: 2.54990
Flash point: 952.3oC
Vapor pressure: 0mmHg at 25°C
Boiling point: 1651oC at 760 mmHg
Appearance properties: easily soluble in 40% ethanol aqueous solution, soluble in water. It is almost insoluble in organic solvents such as ethers, ketones, esters, and hydrocarbons.
Storage conditions: 2-8°C
Solubility: H2O: 50 mg/mL
Use 1: Polymyxin B is an anti-Gram-negative bacillus polypeptide antibiotic, which can change the membrane structure to leak small molecules and inhibit the growth of Gram-negative bacteria. Has a bactericidal effect on E. coli. Binds to the lipid A portion of bacterial lipopolysaccharides. Induces small holes in the outer cell membrane. Mode of action: Combine and interfere with the permeability of the cell plasma membrane. Antibacterial spectrum: Gram-negative bacteria.
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